Overview

What they do
A100x Ventures was founded by Nisa Amoils and Sal Ternullo to back founders building the next generation of internet applications. The firm distinguishes itself by explicitly steering past the "speculation and hype" often associated with Web3, focusing instead on tangible, real-world applications of blockchain and AI technologies. Positioned as a highly operational and compliance-savvy partner, A100x leverages its leadership's deep background in securities law, Big 4 digital asset advisory, and institutional finance to help startups navigate complex regulatory and technical landscapes. They have built a strong reputation in the ecosystem for backing foundational infrastructure and middleware companies that bridge traditional systems with decentralized technologies.
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What they look for
A100x invests in early-stage companies utilizing blockchain and artificial intelligence to build the next wave of internet applications for both consumers and the enterprise. Their core thesis revolves around the convergence of these two frontier technologies to reshape failing systems, create meaningful value, and solve real-world problems.
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Stage
Pre-seed, Seed, Series A
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Sectors
Fintech, AI, SaaS, Mobility and logistics, Healthcare, Climate, Media, Proptech
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Based
New York City, US
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Sources

2026-08-26a100x.vcWe are a venture capital firm backing founders building the technologies of tomorrow.
2026-08-26a100x.vc...investing in frontier technologies including blockchain and AI.
2026-08-26a100x.vcPortfolio Companies

Portfolio, cheque size and the rest

The 23 companies they have backed that we can see, the cheque they write, and whether they are deploying right now.

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